Not that many people are interested in tackling the ascent of Tupungato, largely due to the attraction its higher neighbour, Aconcagua. However, my expedition to Tupungato turned out to be a fabulous adventure, and this volcano deserves to be thought of as one of the Andes' best-kept secrets.
Experienced teams are available to take you to Tupungato from Mendoza, or from the town of Tupungato itself. With the approach from Mendoza quite boring and tedious, the latter option is the better one. Which ever way you choose, however, you'll need to do part of the trip by jeep as some of the rivers are completely impassable on foot.
The most interesting alternative option for those who don't wish to climb up to Tupungato's summit is the ascent of Tupungatito, the extinct volcano's little brother, within which the magmatic activity is today to be found. Its crater is filled with an acid lake and you can observe mild volcanic activity there (Tupungatito hasn't erupted since 1986).